Monday, 17 March 2014

CSIR Lifesciences June 2011 part B solved



21. Recent Studies on Archae suggest that life could have originated

1. extra terrestrially and seeded through meteorite impacts.
2. in shallow coastal areas.
3. in deep hydrothermal vents.
4. in hot, terrestrial habitats.



22. If the ratio of the number of nonsynonymous to synonymous substitutions per site in protein coding gene is greater than one, it is an evidence of selection that is
1. positive
2. negative
3. neutral
4. random

23. The following is the biochemical pathway for purple pigment production in flowers of sweet pea: Recessive mutation of either gene A or B leads to the formation of white flowers. A cross is made between two parents with the genotype: AaBb x aabb. Considering that the two genes are not linked, the phenotypes of the expected progenies are

1. 9 purple: 7 white.
2. 3 white : 1 purple.
3. 1 purple: 1 white.
4. 9 purple: 6 light purple: 1 white.


24. The frequencies of alleles 'A' and 'a' in a population at Hardy-Weinburg equilibrium are 0.7 and 0.3, respectively. In a random sample of 250 individuals taken from the population, how many are
expected to be heterozygous?

1. 112
2. 81
3. 105
4.145


25. The transition to flowering in plants requires

1. growth of plants under long- day conditions.
2. growth of plant under short- day conditions.
3. reprogramming of the shoot apical meristem
4. synthesis of the flowering hormone florigen.





26. In an altruistic act. if a donor sacrifices ‘C’offspring which sthe recipient to gain 'B' offspring and the donor is related to the recipient by a coefficient γ. Under which condition would kin
selection favor this altruistic trait?

l. B > C
2. B > γC
3. γB - C = 0
4. γB - C > 0

27. Aneuploid females with only one X chromosome is a characteristic of individuals with
1. Cri du chat syndrome
2. Klinefelter syndrome
3. Down syndrome
4. Turner syndrome

28. Which of the following food crops has recently been genetically engineered to o in edible vaccine to develop immunity against hepatitis B?
1. Banana
2. Maize
3. Potato
4. Tomato

29. The most commonly used method of estimating primary productivity of a pond involves measurement of the amount of
1. CO2 utilized.
2. autotroph biomass.
3. Oxygen released.
4. Organic carbon

30. The area of allowed regions in the Ramachandran map will be least for
1. Gly.
2. L-Ala.
3. L-Prol.
4. a-methyl L-valine.

31. Small RNAs with internally complementary sequences that form hairpin-like structure, synthesized as precursor RNAs and cleaved by endonucleases to form short duplexes are called
1. snRNA.
2. mRNA.
3. tRNA.
4. miRNA.

32. A much greater proportion of energy fixed by autotrophs is transferred to the herbivore level III the open ocean ecosystem than in a forest ecosystem because
1. aquatic autotrophs are small.
2. aquatic herbivores are more efficient feeders.
3. terrestrial autotrophs are less efficient feeders.
4. terrestrial autotrophs have more indigestible tissues.


33. Polar bears maintain their body temperature because they have more of
1. transducin protein.
2. uncoupling protein.
3. myoglobin protein.
4. FoF1 ATPase.

34. Transport of water across aquaporins is regulated by the presence of which of the following sequence of three highly conserved amino acids?
1. Ala-Asn-Pro.
2. Pro-Asn-Ala.
3. Asn-Pro-Ala.
4. Pro-Ala-Asn.

35. Which of the cyclins have/has essential functions in S-phase of cell cycle?
1. A-type.
2. B-type.
3. D-type.
4. Both B and D-types.

36. During generation of an action potential, depolarization is due to
1. K+ efflux.
2. Na+ efflux.
3. Na+ influx.
4. K+ influx.

37. G protein-linked receptors are transmembrane proteins of
1. single-pass.
2. three-pass.
3. five-pass.
4. seven-pass.

38. Release of nutrients, oxidants or electron donors into the environment to stimulate naturally occurring microorganisms to degrade a contaminant, is referred to as
1. biostimulation.
2. phytoremediation.
3. bioaugmentation.
4. bioremediation.

39. A mechanism that can cause a gene to move from one linkage group to another is
1. crossing over.
2. inversion.
3. translocation.
4. duplication.

40. Th2 response is generated and maintained mainly by which of the following pair of cytokines?
1. IL-4 and IL-10.
2. IL-12 and IFN-γ.
3. IFN-γ and TNF-a.
4. IL-2 and IL-I2.

41. Cytoplasmic detern1inants coding for anterior structure of Drosophila embryo, if injected elsewhere in the recipient embryo, would lead to
1. normal development
2. Formation of additional ectopic head.
3. degeneration
4. a phenotype with two heads and two tails

42. The dwarf pea mutant (le) used by Mendel was defective in which of the following enzyme involved gibberellin biosynthesis?
1. ent-Kaurene synthase.
2. GA 3β-hydroxylase.
3. GA 20-oxidase.
4. ent-Kaurenoic acid hydroxylase.

43. ELISA assay uses
1. an enzyme which can react with secondary antibody.
2. an enzyme which can react with the antigen.
3. a substrate which gets converted into a colored product.
4. a radiolabelled secondary antibody.

44. Which of the following molecules is involved in Ca2+-dependent cell-cell adhesion?
1. Calmodulin
2. Cadherin
3. N-CAM
4. Calpain

45. The 5' Cap of RNA is required for the
1. stability of RNA only.
2. stability and transport of RNA.
3. transport of RNA only.
4. methylation of RNA.

46. Yeast artificial chromosome (YAC) vectors contain selectable markers. Loss of which marker at the cloning site distinguishes the religated YACs from the original vector marker?
1. TRP1
2. SUP4
3 URa3
4.CEN

47. In amphibian oocyte, the germplasm which gets segregated during cleavage to give rise to primordial germ cells (PGC's) is normally
1. distributed evenly throughout the oocyte.
2. localized at animal pole.
3. localized at vegetal pole.
4. aggregated in central part of oocyte.

48. Which of the following statements with respect to alternate oxidase activity in cyanide- resistant respiration in plants, is not correct?
1. Alternate oxidase accepts electrons directly from cytochrome C
2. Some plants exhibit thermogenesis during inflorescene development.
3. Transcription of alternate oxidase gene is often induced by various abiotic stresses
4. When electrons pass to alternate oxidase, two sites of proton pumping are bypassed.

49. In mature Arabidopsis embryo, root apical meristem consists of cells derived from
1. embryo and apical suspensor cell.
2. embryo only.
3. suspensor only.
4. hypophysis only

50. Na+-K+ ATPase is a tetramer of 2α and 2β subunits. On which of the following subunits are the Na+ and K+ binding sites present?
1. both on α
2. both on β
3. Na+ on α and K+ on β
4. Na+ on β and K+ on α

51. A mother of blood group O has a group O child. The father could be of blood type
1. A or B or O.
2. O only.
3. A or B.
4. AB only.

52. Following figure shows McArthur and Wilson's equilibrium model of biota on a single island. In this figure, terms A, B, C and D in order are
1. extinction, immigration, equilibrium number of species, size of species pool.
2. immigration, extinction, equilibrium number of species, size of species pool.
3. extinction, immigration, size of species pool, equilibrium number of species.
4. immigration, extinction, size of species pool, equilibrium number of species.

53. Routinely used glucose biosensor estimates blood glucose level by sensing the concentration of
1. glucose.
2. oxygen.
3. δ-gluconolactone.
4. H2O2

54. Name the ectothermic animal that can thermoregulate by behavioural means rather than by physiological means.
1. Bumble bee in an orchard.
2. Tuna fish in the Ocean.
3. Lizard in a desert.
4. Flatworm in a pond.

55. Which of the following methods of plant transformation can be used to introduce a gene into chloroplast genome?
1. Agrobacterium-mediated transformation
2. Particle delivery system
3. Permeabilization
4. Electroporation

56. The μ and σ of wing length (a normally distributed parameter) in a population of fruit flies are 4 and 0.2 mm, respectively. In a random sample of 400 fruit flies, how many individuals are expected to have wing lengths greater than 4.4 mm?
1. 20
2. 64
3. 10
4. 336

57. Which of the following is a characteristic of an early seral community?
1. Narrow niche specialization.
2. High species diversity .
3. Low community production.
4. Open mineral cycling.

58. A culture of an E. coli strain that is lysogenic for phage lambda is grown at 32°C. Induction of the prophage from the host chromosome will occur when the culture is exposed to
1. 40°C.
2. ultra violet radiation.
3. infra red radiation.
4. wild type E. coli culture

59. During urine formation, the filtration of blood at the glomerulus is
1. an active process.
2. an osmotic process.
3. a pressure-dependent physical process.
4. a non energy - mediated transport process.

60. If the core body temperature of a human rises above normal, which of the following processes would be initiated sequentially for Thermo-regulation?
1. Peripheral vasodilatation, increased rate of respiration, tachycardia.
2. Peripheral Vasoconstriction, increased rate of respiration, bradycardia.
3. Peripheral vasodilatation, decreased rate of respiration, tachycardia.
4. Peripheral vasodilatation, decreased rate of respiration, bradycardia.

61 With which protein of Yersinia would integrin proteins of mammalian cells interact for internalization?
1. Pilin
2. Fimbrin
3. Invasin
4. Adherin

62.Graves disease is associated with
1. insufficiency of thyroid hormones.
2. excess of thyroid hormones.
3. insufficiency of corticosteroids.
4. excess of growth hormones.

63. The fidelity of replicative base selection can be reduced by a factor of 102 when the repair of DNA synthesis involves
1. AP endonuclease.
2. ABC exinuclease.
3. DNA photolyase.
4.TLS DNA polymerase.

64. What is the minimum number of NTPs required for the fom1ation of one peptide bond during protein synthesis?
1. One
2. Two
3. Four
4. Six


65. 'Imperfect fungi' is a group represented by fungal species which have
1. simple mycelia.
2. no known mechanisms of sexual reproduction.
3. unkown phylogenetic relationship.
4. lost its survival mechanism against harsh environments.


66. The photoreceptor commonly involved in light entrainment of the biological clock in flies, moulds and plants is
1. phytochrome.
2. rhodopsin.
3. carotenoid.
4. cryptochrome.


67. The free energy ΔG of a dissolved solute
1. increases with solute concentration
2. decreases with solute concentration
3. is independent of solute concentration
4. depends only on temperature.


68. Which of the following is not a characteristic of phylum Chordata?
1. Pharyngeal slits
2. Amniotic egg
3. Postanal tail
4. Notochord


69. In India, brown antlered deer (sangai) is found only in the floating landmasses of
1. Wular lake.
2. Sasthamkotta lake.
3. Dallake.
4. Lok Tak lake.


70. Both halophytes and glycophytes compartmentalize toxic ions into the intracellular compartment or actively pump them out of the cell to the apoplasts with the  of membrane transport proteins. Among these, the Na+ - H+ antiporter, NHX 1, is localized in the
1. plasma membrane.
2. chloroplast (inner envelope).
3. mitochondria (outer membrane).
4. tonoplast.

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